In a context with limited attention to mental health and prevalent sexual prejudice, valid measurements are a key first step to understanding the psychological suffering of sexual minority populations. We adapted the Patient Health Questionnaire as a depressive symptom severity measure for Vietnamese sexual minority women, ensuring its cultural relevance and suitability for internet-based research. Psychometric evaluation found that the scale is mostly unidimensional and has good convergent validity, good external construct validity, and excellent reliability. Research from North America and Europe provides ample evidence that lesbian, gay and bisexual LGB persons suffer higher rates of psychological distress, depression and suicidality compared to heterosexuals see meta-analyses by King et al.